2int

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2int]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2INT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2INT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2int]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2INT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2INT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2int FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2int OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2int RCSB], [http://www.ebi.ac.uk/pdbsum/2int PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2int FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2int OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2int RCSB], [http://www.ebi.ac.uk/pdbsum/2int PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/IL4_HUMAN IL4_HUMAN]] Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:[http://omim.org/entry/601367 601367]]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.<ref>PMID:14681304</ref>
[[http://www.uniprot.org/uniprot/IL4_HUMAN IL4_HUMAN]] Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:[http://omim.org/entry/601367 601367]]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.<ref>PMID:14681304</ref>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bugg, C E.]]
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[[Category: Bugg, C E]]
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[[Category: Cook, W J.]]
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[[Category: Cook, W J]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick, S E]]
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[[Category: Junior, R Cameron.]]
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[[Category: Junior, R Cameron]]
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[[Category: Junior, R L.Walter.]]
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[[Category: Junior, R L.Walter]]
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[[Category: Nagabhushan, T L.]]
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[[Category: Nagabhushan, T L]]
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[[Category: Reichert, P.]]
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[[Category: Reichert, P]]
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[[Category: Trotta, P P.]]
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[[Category: Trotta, P P]]
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[[Category: Walter, M R.]]
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[[Category: Walter, M R]]
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[[Category: Zhao, B G.]]
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[[Category: Zhao, B G]]
[[Category: Cytokine]]
[[Category: Cytokine]]

Revision as of 09:19, 16 January 2015

CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-4

2int, resolution 2.35Å

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