2pbr
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2pbr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PBR FirstGlance]. <br> | <table><tr><td colspan='2'>[[2pbr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PBR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pbr RCSB], [http://www.ebi.ac.uk/pdbsum/2pbr PDBsum], [http://www.topsan.org/Proteins/RSGI/2pbr TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pbr RCSB], [http://www.ebi.ac.uk/pdbsum/2pbr PDBsum], [http://www.topsan.org/Proteins/RSGI/2pbr TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KTHY_AQUAE KTHY_AQUAE]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Aquifex aeolicus]] | [[Category: Aquifex aeolicus]] | ||
[[Category: DTMP kinase]] | [[Category: DTMP kinase]] | ||
| - | [[Category: Ebihara, A | + | [[Category: Ebihara, A]] |
| - | [[Category: Jeyakanthan, J | + | [[Category: Jeyakanthan, J]] |
| - | [[Category: Kanaujia, S P | + | [[Category: Kanaujia, S P]] |
| - | [[Category: Kuramitsu, S | + | [[Category: Kuramitsu, S]] |
| - | [[Category: Nakagawa, N | + | [[Category: Nakagawa, N]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Ranjani, C Vasuki | + | [[Category: Ranjani, C Vasuki]] |
| - | [[Category: Sekar, K | + | [[Category: Sekar, K]] |
| - | [[Category: Shinkai, A | + | [[Category: Shinkai, A]] |
| - | [[Category: Shiro, Y | + | [[Category: Shiro, Y]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
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[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
[[Category: Nucleotide biosynthesis]] | [[Category: Nucleotide biosynthesis]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Tmp-binding]] | [[Category: Tmp-binding]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 03:12, 25 December 2014
Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
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Categories: Aquifex aeolicus | DTMP kinase | Ebihara, A | Jeyakanthan, J | Kanaujia, S P | Kuramitsu, S | Nakagawa, N | Structural genomic | Ranjani, C Vasuki | Sekar, K | Shinkai, A | Shiro, Y | Yokoyama, S | Atp-binding | Kinase | National project on protein structural and functional analyse | Nppsfa | Nucleotide biosynthesis | Rsgi | Tmp-binding | Transferase
