2osa
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2osa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSA FirstGlance]. <br> | <table><tr><td colspan='2'>[[2osa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSA FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHN1, ARHGAP2, CHN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHN1, ARHGAP2, CHN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2osa RCSB], [http://www.ebi.ac.uk/pdbsum/2osa PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2osa RCSB], [http://www.ebi.ac.uk/pdbsum/2osa PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/CHIN_HUMAN CHIN_HUMAN]] Defects in CHN1 are the cause of Duane retraction syndrome type 2 (DURS2) [MIM:[http://omim.org/entry/604356 604356]]. Duane retraction syndrome is a congenital eye movement disorder characterized by a failure of cranial nerve VI (the abducens nerve) to develop normally, resulting in restriction or absence of abduction, adduction, or both, and narrowing of the palpebral fissure and retraction of the globe on attempted adduction. Undiagnosed in children, it can lead to amblyopia, a permanent uncorrectable loss of vision. | [[http://www.uniprot.org/uniprot/CHIN_HUMAN CHIN_HUMAN]] Defects in CHN1 are the cause of Duane retraction syndrome type 2 (DURS2) [MIM:[http://omim.org/entry/604356 604356]]. Duane retraction syndrome is a congenital eye movement disorder characterized by a failure of cranial nerve VI (the abducens nerve) to develop normally, resulting in restriction or absence of abduction, adduction, or both, and narrowing of the palpebral fissure and retraction of the globe on attempted adduction. Undiagnosed in children, it can lead to amblyopia, a permanent uncorrectable loss of vision. | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Hong, B S | + | [[Category: Hong, B S]] |
| - | [[Category: Park, H W | + | [[Category: Park, H W]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Shen, L | + | [[Category: Shen, L]] |
| - | [[Category: Sundstrom, M | + | [[Category: Sundstrom, M]] |
| - | [[Category: Walker, J R | + | [[Category: Walker, J R]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Gtpase activation]] | [[Category: Gtpase activation]] | ||
[[Category: Rho-gap]] | [[Category: Rho-gap]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
Revision as of 15:36, 19 January 2015
The Rho-GAP domain of human N-chimaerin
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