This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ppi
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ppi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PPI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PPI FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ppi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PPI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PPI FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAN, GAN1, KLHL16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAN, GAN1, KLHL16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ppi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ppi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ppi RCSB], [http://www.ebi.ac.uk/pdbsum/2ppi PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ppi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ppi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ppi RCSB], [http://www.ebi.ac.uk/pdbsum/2ppi PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/GAN_HUMAN GAN_HUMAN]] Defects in GAN are the cause of giant axonal neuropathy (GAN) [MIM:[http://omim.org/entry/256850 256850]]. GAN is a severe autosomal recessive sensorimotor neuropathy affecting both the peripheral nerves and the central nervous system. It is characterized by neurofilament accumulation, leading to segmental distention of axons.<ref>PMID:16303566</ref> <ref>PMID:11062483</ref> <ref>PMID:11971098</ref> <ref>PMID:12655563</ref> <ref>PMID:17578852</ref> <ref>PMID:17587580</ref> | [[http://www.uniprot.org/uniprot/GAN_HUMAN GAN_HUMAN]] Defects in GAN are the cause of giant axonal neuropathy (GAN) [MIM:[http://omim.org/entry/256850 256850]]. GAN is a severe autosomal recessive sensorimotor neuropathy affecting both the peripheral nerves and the central nervous system. It is characterized by neurofilament accumulation, leading to segmental distention of axons.<ref>PMID:16303566</ref> <ref>PMID:11062483</ref> <ref>PMID:11971098</ref> <ref>PMID:12655563</ref> <ref>PMID:17578852</ref> <ref>PMID:17587580</ref> | ||
| Line 25: | Line 25: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Amos, A | + | [[Category: Amos, A]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bullock, A | + | [[Category: Bullock, A]] |
| - | [[Category: Burgess-Brown, N | + | [[Category: Burgess-Brown, N]] |
| - | [[Category: Debreczeni, J E | + | [[Category: Debreczeni, J E]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Keates, T | + | [[Category: Keates, T]] |
| - | [[Category: Knapp, S | + | [[Category: Knapp, S]] |
| - | [[Category: Papagrigoriou, E | + | [[Category: Papagrigoriou, E]] |
| - | [[Category: Pike, A C.W | + | [[Category: Pike, A C.W]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Savitsky, P | + | [[Category: Savitsky, P]] |
| - | [[Category: Sundstrom, M | + | [[Category: Sundstrom, M]] |
| - | [[Category: Tickle, J | + | [[Category: Tickle, J]] |
| - | [[Category: Turnbull, A P | + | [[Category: Turnbull, A P]] |
| - | [[Category: Ugochukwu, E | + | [[Category: Ugochukwu, E]] |
| - | [[Category: Umeano, C | + | [[Category: Umeano, C]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Btb domain]] | [[Category: Btb domain]] | ||
[[Category: Protein degradation]] | [[Category: Protein degradation]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
Revision as of 17:23, 19 January 2015
Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin
| |||||||||||
Categories: Homo sapiens | Amos, A | Arrowsmith, C H | Bullock, A | Burgess-Brown, N | Debreczeni, J E | Delft, F von | Edwards, A | Keates, T | Knapp, S | Papagrigoriou, E | Pike, A C.W | Structural genomic | Savitsky, P | Sundstrom, M | Tickle, J | Turnbull, A P | Ugochukwu, E | Umeano, C | Weigelt, J | Btb domain | Protein degradation | Sgc | Structural protein
