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2rqm
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2rqm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQM FirstGlance]. <br> | <table><tr><td colspan='2'>[[2rqm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQM FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rqk|2rqk]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rqk|2rqk]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mesdc2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mesdc2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqm RCSB], [http://www.ebi.ac.uk/pdbsum/2rqm PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqm RCSB], [http://www.ebi.ac.uk/pdbsum/2rqm PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MESD2_MOUSE MESD2_MOUSE]] Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.<ref>PMID:12581525</ref> <ref>PMID:21397183</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Andersen, O M | + | [[Category: Andersen, O M]] |
| - | [[Category: Diehl, A | + | [[Category: Diehl, A]] |
| - | [[Category: Holdener, B C | + | [[Category: Holdener, B C]] |
| - | [[Category: Koehler, C | + | [[Category: Koehler, C]] |
| - | [[Category: Lighthouse, J K | + | [[Category: Lighthouse, J K]] |
| - | [[Category: Oschkinat, H | + | [[Category: Oschkinat, H]] |
| - | [[Category: Schmieder, P | + | [[Category: Schmieder, P]] |
| - | [[Category: Werther, T | + | [[Category: Werther, T]] |
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
Revision as of 19:01, 25 December 2014
NMR Solution Structure of Mesoderm Development (MESD) - open conformation
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