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2w0t
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w0t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0T FirstGlance]. <br> | <table><tr><td colspan='2'>[[2w0t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0T FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0t RCSB], [http://www.ebi.ac.uk/pdbsum/2w0t PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0t RCSB], [http://www.ebi.ac.uk/pdbsum/2w0t PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LMBL2_HUMAN LMBL2_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.<ref>PMID:19233876</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Allen, M D | + | [[Category: Allen, M D]] |
| - | [[Category: Bycroft, M | + | [[Category: Bycroft, M]] |
| - | [[Category: Lechtenberg, B C | + | [[Category: Lechtenberg, B C]] |
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
[[Category: Lmbl2]] | [[Category: Lmbl2]] | ||
Revision as of 22:15, 25 December 2014
SOLUTION STRUCTURE OF THE FCS ZINC FINGER DOMAIN OF HUMAN LMBL2
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Categories: Homo sapiens | Allen, M D | Bycroft, M | Lechtenberg, B C | Chromatin regulator | Lmbl2 | Mbt repeat | Metal-binding | Mym zinc finger | Nucleus | Pcg protein | Phosphoprotein | Polycomb group | Rna binding | Transcription | Transcription regulation | Treble clef fold | Yacg | Zinc-finger

