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2ver
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ver]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VER OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VER FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ver]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VER OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VER FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTN:S-[(1-OXYL-2,2,5,5-TETRAMETHYL-2,5-DIHYDRO-1H-PYRROL-3-YL)METHYL]+METHANESULFONOTHIOATE'>MTN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTN:S-[(1-OXYL-2,2,5,5-TETRAMETHYL-2,5-DIHYDRO-1H-PYRROL-3-YL)METHYL]+METHANESULFONOTHIOATE'>MTN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e07|1e07]], [[1ut2|1ut2]], [[1usz|1usz]], [[2ixq|2ixq]], [[1rxl|1rxl]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e07|1e07]], [[1ut2|1ut2]], [[1usz|1usz]], [[2ixq|2ixq]], [[1rxl|1rxl]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ver FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ver OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ver RCSB], [http://www.ebi.ac.uk/pdbsum/2ver PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ver FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ver OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ver RCSB], [http://www.ebi.ac.uk/pdbsum/2ver PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AFAE3_ECOLX AFAE3_ECOLX]] Hemagglutinins of uropathogenic E.coli mediate adherence to the upper urinary tract. These adhesins bind to the Dr blood group antigen and also agglutinate human erythrocytes in the presence of D-mannose (mannose-resistant hemagglutination (MRHA)). [[http://www.uniprot.org/uniprot/CEAM5_HUMAN CEAM5_HUMAN]] Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.<ref>PMID:10864933</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Cota, E | + | [[Category: Cota, E]] |
| - | [[Category: Demeler, B | + | [[Category: Demeler, B]] |
| - | [[Category: Korotkova, N | + | [[Category: Korotkova, N]] |
| - | [[Category: Marchant, J | + | [[Category: Marchant, J]] |
| - | [[Category: Matthews, S | + | [[Category: Matthews, S]] |
| - | [[Category: Moseley, S L | + | [[Category: Moseley, S L]] |
| - | [[Category: Stenkamp, R E | + | [[Category: Stenkamp, R E]] |
| - | [[Category: Thomas, W E | + | [[Category: Thomas, W E]] |
| - | [[Category: Trong, I Le | + | [[Category: Trong, I Le]] |
| - | [[Category: Yang, Y | + | [[Category: Yang, Y]] |
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Cell projection]] | [[Category: Cell projection]] | ||
Revision as of 19:25, 25 December 2014
STRUCTURAL MODEL FOR THE COMPLEX BETWEEN THE DR ADHESINS AND CARCINOEMBRYONIC ANTIGEN (CEA)
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