2v9z

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2v9z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9Z FirstGlance]. <br>
<table><tr><td colspan='2'>[[2v9z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9Z FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v9z RCSB], [http://www.ebi.ac.uk/pdbsum/2v9z PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v9z RCSB], [http://www.ebi.ac.uk/pdbsum/2v9z PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Haloalkane dehalogenase]]
[[Category: Haloalkane dehalogenase]]
[[Category: Rhodococcus rhodochrous]]
[[Category: Rhodococcus rhodochrous]]
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[[Category: Chovancova, E.]]
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[[Category: Chovancova, E]]
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[[Category: Damborsky, J.]]
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[[Category: Damborsky, J]]
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[[Category: Emmer, J.]]
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[[Category: Emmer, J]]
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[[Category: Jesenska, A.]]
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[[Category: Jesenska, A]]
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[[Category: Koudelakova, T.]]
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[[Category: Koudelakova, T]]
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[[Category: Lapkouski, M.]]
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[[Category: Lapkouski, M]]
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[[Category: Monincova, M.]]
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[[Category: Monincova, M]]
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[[Category: Nagata, Y.]]
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[[Category: Nagata, Y]]
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[[Category: Prokop, Z.]]
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[[Category: Prokop, Z]]
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[[Category: Sato, Y.]]
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[[Category: Sato, Y]]
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[[Category: Senda, T.]]
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[[Category: Senda, T]]
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[[Category: Smatanova, I Kuta.]]
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[[Category: Smatanova, I Kuta]]
[[Category: Detoxification]]
[[Category: Detoxification]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 15:40, 25 December 2014

STRUCTURE OF THE RHODOCOCCUS HALOALKANE DEHALOGENASE MUTANT WITH ENHANCED ENANTIOSELECTIVITY

2v9z, resolution 3.00Å

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