2wou

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wou]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOU FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wou]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZZF:4-({4-[(2,6-DIMETHYLPYRIDIN-3-YL)OXY]PYRIDIN-2-YL}AMINO)BENZENESULFONAMIDE'>ZZF</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZZF:4-({4-[(2,6-DIMETHYLPYRIDIN-3-YL)OXY]PYRIDIN-2-YL}AMINO)BENZENESULFONAMIDE'>ZZF</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1py5|1py5]], [[1ias|1ias]], [[1b6c|1b6c]], [[1vjy|1vjy]], [[1rw8|1rw8]], [[2wot|2wot]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1py5|1py5]], [[1ias|1ias]], [[1b6c|1b6c]], [[1vjy|1vjy]], [[1rw8|1rw8]], [[2wot|2wot]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wou OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wou RCSB], [http://www.ebi.ac.uk/pdbsum/2wou PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wou OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wou RCSB], [http://www.ebi.ac.uk/pdbsum/2wou PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Receptor protein serine/threonine kinase]]
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[[Category: Debreczeni, J E.]]
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[[Category: Debreczeni, J E]]
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[[Category: Dishington, A P.]]
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[[Category: Dishington, A P]]
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[[Category: Finlay, R.]]
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[[Category: Finlay, R]]
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[[Category: Gingell, H J.]]
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[[Category: Gingell, H J]]
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[[Category: Goldberg, F W.]]
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[[Category: Goldberg, F W]]
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[[Category: Norman, R A.]]
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[[Category: Norman, R A]]
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[[Category: Powell, S J.]]
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[[Category: Powell, S J]]
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[[Category: Roberts, A L.]]
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[[Category: Roberts, A L]]
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[[Category: Roberts, N J.]]
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[[Category: Roberts, N J]]
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[[Category: Ward, R A.]]
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[[Category: Ward, R A]]
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[[Category: Wickson, K F.]]
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[[Category: Wickson, K F]]
[[Category: Alk]]
[[Category: Alk]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]

Revision as of 09:24, 20 January 2015

ALK5 IN COMPLEX WITH 4-((4-((2,6-DIMETHYL-3-PYRIDYL)OXY)-2-PYRIDYL)AMINO)BENZENESULFONAMIDE

2wou, resolution 2.30Å

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