2uyd

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2uyd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2uyd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYD FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b2v|1b2v]], [[1dk0|1dk0]], [[1dkh|1dkh]], [[1ybj|1ybj]], [[2cn4|2cn4]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b2v|1b2v]], [[1dk0|1dk0]], [[1dkh|1dkh]], [[1ybj|1ybj]], [[2cn4|2cn4]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyd RCSB], [http://www.ebi.ac.uk/pdbsum/2uyd PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyd RCSB], [http://www.ebi.ac.uk/pdbsum/2uyd PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/HASA_SERMA HASA_SERMA]] Can bind free heme and also acquire it from hemoglobin. Conveys heme from hemoglobin to the HasR receptor which releases it into the bacterium. HasR alone can take up heme but the synergy between HasA and HasR increases heme uptake 100-fold.<ref>PMID:7937909</ref> <ref>PMID:9171402</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Serratia marcescens]]
[[Category: Serratia marcescens]]
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[[Category: Caillet-Saguy, C.]]
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[[Category: Caillet-Saguy, C]]
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[[Category: Czjzek, M.]]
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[[Category: Czjzek, M]]
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[[Category: Fournelle, A.]]
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[[Category: Fournelle, A]]
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[[Category: Guigliarelli, B.]]
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[[Category: Guigliarelli, B]]
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[[Category: Izadi-Pruneyre, N.]]
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[[Category: Izadi-Pruneyre, N]]
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[[Category: Lecroisey, A.]]
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[[Category: Lecroisey, A]]
[[Category: Heme]]
[[Category: Heme]]
[[Category: Heme acquisition system]]
[[Category: Heme acquisition system]]

Revision as of 16:00, 25 December 2014

CRYSTAL STRUCTURE OF THE SMHASA MUTANT H83A

2uyd, resolution 2.70Å

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