4qox
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4qox]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QOX FirstGlance]. <br> | <table><tr><td colspan='2'>[[4qox]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QOX FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXR:3-(3-BROMOBENZYL)-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>DXR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXR:3-(3-BROMOBENZYL)-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>DXR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qox RCSB], [http://www.ebi.ac.uk/pdbsum/4qox PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qox RCSB], [http://www.ebi.ac.uk/pdbsum/4qox PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CDPK4_PLAF7 CDPK4_PLAF7]] Calcium-dependent kinase that plays a central role in the sexual reproduction and mosquito transmission of P.falciparum. Required for cell cycle progression in the male gametocyte, an essential step in parasite transmission to the mosquito (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Amani, M | + | [[Category: Amani, M]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: He, H | + | [[Category: He, H]] |
| - | [[Category: Hui, R | + | [[Category: Hui, R]] |
| - | [[Category: Hutchinson, A | + | [[Category: Hutchinson, A]] |
| - | [[Category: Lin, Y H | + | [[Category: Lin, Y H]] |
| - | [[Category: Loppnau, P | + | [[Category: Loppnau, P]] |
| - | [[Category: Lovato, D V | + | [[Category: Lovato, D V]] |
| - | [[Category: Neculai, M | + | [[Category: Neculai, M]] |
| - | [[Category: Ravichandran, M | + | [[Category: Ravichandran, M]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Seitova, A | + | [[Category: Seitova, A]] |
| - | [[Category: Walker, J R | + | [[Category: Walker, J R]] |
| - | [[Category: Wernimont, A K | + | [[Category: Wernimont, A K]] |
[[Category: Cdpk]] | [[Category: Cdpk]] | ||
[[Category: Malaria]] | [[Category: Malaria]] | ||
[[Category: Plasmodium]] | [[Category: Plasmodium]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 08:35, 24 December 2014
Crystal Structure of CDPK4 from Plasmodium Falciparum, PF3D7_0717500
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Categories: Non-specific serine/threonine protein kinase | Amani, M | Arrowsmith, C H | Bountra, C | Edwards, A M | He, H | Hui, R | Hutchinson, A | Lin, Y H | Loppnau, P | Lovato, D V | Neculai, M | Ravichandran, M | Structural genomic | Seitova, A | Walker, J R | Wernimont, A K | Cdpk | Malaria | Plasmodium | Sgc | Transferase
