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4rci

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4rci]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RCI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4rci]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RCI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rcj|4rcj]], [[4rcm|4rcm]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rcj|4rcj]], [[4rcm|4rcm]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rci RCSB], [http://www.ebi.ac.uk/pdbsum/4rci PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rci RCSB], [http://www.ebi.ac.uk/pdbsum/4rci PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Liu, K.]]
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[[Category: Liu, K]]
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[[Category: Min, J.]]
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[[Category: Min, J]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Tempel, W.]]
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[[Category: Tempel, W]]
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[[Category: Walker, J R.]]
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[[Category: Walker, J R]]
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[[Category: Xu, C.]]
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[[Category: Xu, C]]
[[Category: Rna binding protein]]
[[Category: Rna binding protein]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 

Revision as of 09:10, 25 December 2014

Crystal structure of YTHDF1 YTH domain

4rci, resolution 1.97Å

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