2x5n

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2x5n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X5N FirstGlance]. <br>
<table><tr><td colspan='2'>[[2x5n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X5N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X5N FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x5n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x5n RCSB], [http://www.ebi.ac.uk/pdbsum/2x5n PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x5n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x5n RCSB], [http://www.ebi.ac.uk/pdbsum/2x5n PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RPN10_SCHPO RPN10_SCHPO]] Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.<ref>PMID:10809753</ref> <ref>PMID:12560082</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Boehringer, J.]]
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[[Category: Boehringer, J]]
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[[Category: Brown, N R.]]
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[[Category: Brown, N R]]
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[[Category: Endicott, J A.]]
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[[Category: Endicott, J A]]
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[[Category: Gehring, K.]]
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[[Category: Gehring, K]]
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[[Category: Gordon, C.]]
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[[Category: Gordon, C]]
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[[Category: Lowe, E D.]]
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[[Category: Lowe, E D]]
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[[Category: Noble, M E.M.]]
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[[Category: Noble, M E.M]]
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[[Category: Riedinger, C.]]
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[[Category: Riedinger, C]]
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[[Category: Trempe, J F.]]
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[[Category: Trempe, J F]]
[[Category: Nuclear protein]]
[[Category: Nuclear protein]]
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Proteasome]]
[[Category: Proteasome]]
[[Category: Ubiquitin]]
[[Category: Ubiquitin]]

Revision as of 04:17, 25 December 2014

CRYSTAL STRUCTURE OF THE SPRPN10 VWA DOMAIN

2x5n, resolution 1.30Å

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