2roo
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2roo]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ROO FirstGlance]. <br> | <table><tr><td colspan='2'>[[2roo]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ROO FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2roo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2roo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2roo RCSB], [http://www.ebi.ac.uk/pdbsum/2roo PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2roo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2roo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2roo RCSB], [http://www.ebi.ac.uk/pdbsum/2roo PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TXMG4_MACGS TXMG4_MACGS]] Selectively slows channel inactivation of mammalian Nav1.1/SCN1A, Nav1.3/SCN3A, and Nav1.6/SCN8A and shows higher affinity for insect Nav1/para channels (site 3). Induces tonic repetitive firing of nerve impulses in insect neurons accompanied by plateau potentials.<ref>PMID:12860384</ref> <ref>PMID:19592486</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Yamaji, N | + | [[Category: Yamaji, N]] |
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Ionic channel inhibitor]] | [[Category: Ionic channel inhibitor]] | ||
Revision as of 07:47, 25 December 2014
Solution structure of Magi4, a spider toxin from Macrothele gigas
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