2wq8
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wq8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQ8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2wq8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQ8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jkx|2jkx]], [[2vz3|2vz3]], [[1gof|1gof]], [[1k3i|1k3i]], [[1t2x|1t2x]], [[1goh|1goh]], [[2vz1|2vz1]], [[1gog|1gog]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jkx|2jkx]], [[2vz3|2vz3]], [[1gof|1gof]], [[1k3i|1k3i]], [[1t2x|1t2x]], [[1goh|1goh]], [[2vz1|2vz1]], [[1gog|1gog]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wq8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wq8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wq8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wq8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wq8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wq8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GAOA_GIBZE GAOA_GIBZE]] Catalyzes the sterospecific oxidation of primary alcohols to the corresponding aldehydes. The biologically relevant substrate of the enzyme is not known as the enzyme exhibits broad substrate specificity from small alcohols through sugars to oligo- and polysaccharides (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Galactose oxidase]] | [[Category: Galactose oxidase]] | ||
[[Category: Gibberella zeae]] | [[Category: Gibberella zeae]] | ||
| - | [[Category: Behrens, C | + | [[Category: Behrens, C]] |
| - | [[Category: Flitsch, S L | + | [[Category: Flitsch, S L]] |
| - | [[Category: Grogan, G J | + | [[Category: Grogan, G J]] |
| - | [[Category: Ioannou, A | + | [[Category: Ioannou, A]] |
| - | [[Category: Rannes, J G | + | [[Category: Rannes, J G]] |
| - | [[Category: Turner, N J | + | [[Category: Turner, N J]] |
| - | [[Category: Willies, S C | + | [[Category: Willies, S C]] |
[[Category: Directed evolution]] | [[Category: Directed evolution]] | ||
[[Category: Glycoengineering]] | [[Category: Glycoengineering]] | ||
Revision as of 15:08, 24 December 2014
GLYCAN LABELLING USING ENGINEERED VARIANTS OF GALACTOSE OXIDASE OBTAINED BY DIRECTED EVOLUTION
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