2of6

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2of6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/West_nile_virus West nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OF6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OF6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2of6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/West_nile_virus West nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OF6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OF6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2of6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2of6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2of6 RCSB], [http://www.ebi.ac.uk/pdbsum/2of6 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2of6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2of6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2of6 RCSB], [http://www.ebi.ac.uk/pdbsum/2of6 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q9Q6P4_WNV Q9Q6P4_WNV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: West nile virus]]
[[Category: West nile virus]]
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[[Category: Chipman, P R.]]
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[[Category: Chipman, P R]]
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[[Category: Kaufmann, B.]]
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[[Category: Kaufmann, B]]
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[[Category: Kuhn, R J.]]
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[[Category: Kuhn, R J]]
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[[Category: Rossmann, M G.]]
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[[Category: Rossmann, M G]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang, Y]]
[[Category: Em immature flavivirus west nile]]
[[Category: Em immature flavivirus west nile]]
[[Category: Icosahedral virus]]
[[Category: Icosahedral virus]]
[[Category: Virus]]
[[Category: Virus]]

Revision as of 13:38, 25 December 2014

Structure of immature West Nile virus

2of6, resolution 24.00Å

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