2zkc

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zkc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZKC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zkc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZKC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPZ:4,4-CYCLOHEXANE-1,1-DIYLDIPHENOL'>BPZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPZ:4,4-CYCLOHEXANE-1,1-DIYLDIPHENOL'>BPZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e2r|2e2r]], [[2zas|2zas]], [[2zbs|2zbs]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2e2r|2e2r]], [[2zas|2zas]], [[2zbs|2zbs]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zkc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zkc RCSB], [http://www.ebi.ac.uk/pdbsum/2zkc PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zkc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zkc RCSB], [http://www.ebi.ac.uk/pdbsum/2zkc PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN]] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Estrogen-related receptor|Estrogen-related receptor]]
*[[Estrogen-related receptor|Estrogen-related receptor]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kakuta, Y.]]
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[[Category: Kakuta, Y]]
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[[Category: Matsushima, A.]]
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[[Category: Matsushima, A]]
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[[Category: Shimohigashi, Y.]]
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[[Category: Shimohigashi, Y]]
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[[Category: Teramoto, T.]]
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[[Category: Teramoto, T]]
[[Category: Activator]]
[[Category: Activator]]
[[Category: Bpa]]
[[Category: Bpa]]

Revision as of 15:19, 24 December 2014

Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z

2zkc, resolution 1.70Å

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