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3c3q

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3c3q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C3Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[3c3q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C3Q FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oew|2oew]], [[3c3o|3c3o]], [[3c3r|3c3r]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oew|2oew]], [[3c3o|3c3o]], [[3c3r|3c3r]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDCD6IP, AIP1, ALIX, KIAA1375 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDCD6IP, AIP1, ALIX, KIAA1375 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c3q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c3q RCSB], [http://www.ebi.ac.uk/pdbsum/3c3q PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c3q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c3q RCSB], [http://www.ebi.ac.uk/pdbsum/3c3q PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/CHM4B_HUMAN CHM4B_HUMAN]] Defects in CHMP4B are the cause of cataract posterior polar type 3 (CTPP3) [MIM:[http://omim.org/entry/605387 605387]]. A subcapsular opacity, usually disk-shaped, located at the back of the lens. It can have a marked effect on visual acuity.<ref>PMID:17701905</ref>
[[http://www.uniprot.org/uniprot/CHM4B_HUMAN CHM4B_HUMAN]] Defects in CHMP4B are the cause of cataract posterior polar type 3 (CTPP3) [MIM:[http://omim.org/entry/605387 605387]]. A subcapsular opacity, usually disk-shaped, located at the back of the lens. It can have a marked effect on visual acuity.<ref>PMID:17701905</ref>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Fisher, R D.]]
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[[Category: Fisher, R D]]
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[[Category: Hill, C P.]]
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[[Category: Hill, C P]]
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[[Category: McCullough, J B.]]
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[[Category: McCullough, J B]]
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[[Category: Sundquist, W I.]]
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[[Category: Sundquist, W I]]
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[[Category: Whitby, F G.]]
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[[Category: Whitby, F G]]
[[Category: Alix chmp4b bro1 amphipathic-helix]]
[[Category: Alix chmp4b bro1 amphipathic-helix]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]

Revision as of 08:32, 20 January 2015

ALIX Bro1-domain:CHMIP4B co-crystal structure

3c3q, resolution 2.10Å

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