3c77

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3c77]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2at4 2at4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C77 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3c77]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2at4 2at4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C77 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDE:FE(III)+DEUTEROPORPHYRIN+IX'>FDE</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDE:FE(III)+DEUTEROPORPHYRIN+IX'>FDE</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2at5|2at5]], [[2at6|2at6]], [[3c78|3c78]], [[1x8p|1x8p]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2at5|2at5]], [[2at6|2at6]], [[3c78|3c78]], [[1x8p|1x8p]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c77 RCSB], [http://www.ebi.ac.uk/pdbsum/3c77 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c77 RCSB], [http://www.ebi.ac.uk/pdbsum/3c77 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Rhodnius prolixus]]
[[Category: Rhodnius prolixus]]
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[[Category: Amoia, A M.]]
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[[Category: Amoia, A M]]
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[[Category: Montfort, W R.]]
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[[Category: Montfort, W R]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Ferric]]
[[Category: Ferric]]

Revision as of 20:48, 25 December 2014

1.08 A crystal structure of nitrophorin 4 from Rhodnius prolixus containing FE(III) deuteroporphyrin ix complexed with ammonia at ph 7.5

3c77, resolution 1.08Å

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