1k9o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1k9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Manduca_sexta Manduca sexta] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1i99 1i99]. The May 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Serpins'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_5 10.2210/rcsb_pdb/mom_2004_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K9O FirstGlance]. <br> | <table><tr><td colspan='2'>[[1k9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Manduca_sexta Manduca sexta] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1i99 1i99]. The May 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Serpins'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_5 10.2210/rcsb_pdb/mom_2004_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K9O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr> | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k9o RCSB], [http://www.ebi.ac.uk/pdbsum/1k9o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k9o RCSB], [http://www.ebi.ac.uk/pdbsum/1k9o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SERA_MANSE SERA_MANSE]] Inhibits elastase. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Serpins]] | [[Category: Serpins]] | ||
[[Category: Trypsin]] | [[Category: Trypsin]] | ||
| - | [[Category: Belmares, R | + | [[Category: Belmares, R]] |
| - | [[Category: Bergstrom, R C | + | [[Category: Bergstrom, R C]] |
| - | [[Category: Cech, A L | + | [[Category: Cech, A L]] |
| - | [[Category: Corey, D R | + | [[Category: Corey, D R]] |
| - | [[Category: Goldsmith, E J | + | [[Category: Goldsmith, E J]] |
| - | [[Category: Kanost, M R | + | [[Category: Kanost, M R]] |
| - | [[Category: Tong, Y | + | [[Category: Tong, Y]] |
| - | [[Category: Ye, S | + | [[Category: Ye, S]] |
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Michaelis serpin-protease complex inhibitory triad]] | [[Category: Michaelis serpin-protease complex inhibitory triad]] | ||
Revision as of 00:03, 25 December 2014
CRYSTAL STRUCTURE OF MICHAELIS SERPIN-TRYPSIN COMPLEX
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