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2wqb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wqb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQB FirstGlance]. <br> | <table><tr><td colspan='2'>[[2wqb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QQ1:2-[3-(CYCLOHEXYLMETHYL)-5-PHENYL-IMIDAZOL-4-YL]-[1,3]THIAZOLO[4,5-E]PYRIMIDIN-7-AMINE'>QQ1</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QQ1:2-[3-(CYCLOHEXYLMETHYL)-5-PHENYL-IMIDAZOL-4-YL]-[1,3]THIAZOLO[4,5-E]PYRIMIDIN-7-AMINE'>QQ1</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gy5|2gy5]], [[1fvr|1fvr]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gy5|2gy5]], [[1fvr|1fvr]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wqb RCSB], [http://www.ebi.ac.uk/pdbsum/2wqb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wqb RCSB], [http://www.ebi.ac.uk/pdbsum/2wqb PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| - | [[Category: Brassington, C | + | [[Category: Brassington, C]] |
| - | [[Category: Breed, J | + | [[Category: Breed, J]] |
| - | [[Category: Buttar, D | + | [[Category: Buttar, D]] |
| - | [[Category: Fitzek, M | + | [[Category: Fitzek, M]] |
| - | [[Category: Forder, C | + | [[Category: Forder, C]] |
| - | [[Category: Hassall, L | + | [[Category: Hassall, L]] |
| - | [[Category: Hayter, B R | + | [[Category: Hayter, B R]] |
| - | [[Category: Jones, C D | + | [[Category: Jones, C D]] |
| - | [[Category: Luke, R W.A | + | [[Category: Luke, R W.A]] |
| - | [[Category: McCall, E | + | [[Category: McCall, E]] |
| - | [[Category: McCoull, W | + | [[Category: McCoull, W]] |
| - | [[Category: McMiken, H | + | [[Category: McMiken, H]] |
| - | [[Category: Norman, R | + | [[Category: Norman, R]] |
| - | [[Category: Paterson, D | + | [[Category: Paterson, D]] |
| - | [[Category: Rowsell, S | + | [[Category: Rowsell, S]] |
| - | [[Category: Tucker, J A | + | [[Category: Tucker, J A]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
Revision as of 11:21, 20 January 2015
Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor
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Categories: Homo sapiens | Receptor protein-tyrosine kinase | Brassington, C | Breed, J | Buttar, D | Fitzek, M | Forder, C | Hassall, L | Hayter, B R | Jones, C D | Luke, R W.A | McCall, E | McCoull, W | McMiken, H | Norman, R | Paterson, D | Rowsell, S | Tucker, J A | Atp-binding | Disease mutation | Glycoprotein | Kinase | Nucleotide-binding | Oncology | Phosphoprotein | Phosphotransferase | Receptor | Thiazolopyrimidine | Transferase | Tyrosine-protein kinase
