2efa

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2efa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2efa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2efa RCSB], [http://www.ebi.ac.uk/pdbsum/2efa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2efa RCSB], [http://www.ebi.ac.uk/pdbsum/2efa PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/INS_PIG INS_PIG]] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Ishikawa, T.]]
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[[Category: Ishikawa, T]]
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[[Category: Niimura, N.]]
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[[Category: Niimura, N]]
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[[Category: Tanaka, I.]]
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[[Category: Tanaka, I]]
[[Category: Cubic porcine insulin]]
[[Category: Cubic porcine insulin]]
[[Category: Hormone]]
[[Category: Hormone]]
[[Category: Hormone-growth factor complex]]
[[Category: Hormone-growth factor complex]]

Revision as of 05:37, 25 December 2014

Neutron crystal structure of cubic insulin at pD6.6

2efa, resolution 2.70Å

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