1e9d

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1e9d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E9D FirstGlance]. <br>
<table><tr><td colspan='2'>[[1e9d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E9D FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e2d|1e2d]], [[1e2e|1e2e]], [[1e2f|1e2f]], [[1e2g|1e2g]], [[1e2q|1e2q]], [[1e98|1e98]], [[1e99|1e99]], [[1e9a|1e9a]], [[1e9b|1e9b]], [[1e9c|1e9c]], [[1e9e|1e9e]], [[1e9f|1e9f]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e2d|1e2d]], [[1e2e|1e2e]], [[1e2f|1e2f]], [[1e2g|1e2g]], [[1e2q|1e2q]], [[1e98|1e98]], [[1e99|1e99]], [[1e9a|1e9a]], [[1e9b|1e9b]], [[1e9c|1e9c]], [[1e9e|1e9e]], [[1e9f|1e9f]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e9d RCSB], [http://www.ebi.ac.uk/pdbsum/1e9d PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e9d RCSB], [http://www.ebi.ac.uk/pdbsum/1e9d PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Human]]
[[Category: Human]]
[[Category: DTMP kinase]]
[[Category: DTMP kinase]]
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[[Category: Brundiers, R.]]
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[[Category: Brundiers, R]]
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[[Category: Goody, R S.]]
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[[Category: Goody, R S]]
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[[Category: Konrad, M.]]
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[[Category: Konrad, M]]
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[[Category: Lavie, A.]]
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[[Category: Lavie, A]]
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[[Category: Ostermann, N.]]
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[[Category: Ostermann, N]]
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[[Category: Padiyar, S.]]
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[[Category: Padiyar, S]]
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[[Category: Reintein, J.]]
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[[Category: Reintein, J]]
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[[Category: Schlichting, I.]]
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[[Category: Schlichting, I]]
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[[Category: Veit, T.]]
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[[Category: Veit, T]]
[[Category: P-loop]]
[[Category: P-loop]]
[[Category: Phosphotransferase]]
[[Category: Phosphotransferase]]
[[Category: Thymidylate kinase]]
[[Category: Thymidylate kinase]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 23:04, 22 December 2014

Mutant human thymidylate kinase (F105Y) complexed with AZTMP and ADP

1e9d, resolution 1.70Å

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