1o6h

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1o6h]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O6H FirstGlance]. <br>
<table><tr><td colspan='2'>[[1o6h]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O6H FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=W37:N-(6-{[1-(4-BROMOPHENYL)ISOQUINOLIN-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE'>W37</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=W37:N-(6-{[1-(4-BROMOPHENYL)ISOQUINOLIN-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE'>W37</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gsz|1gsz]], [[1h35|1h35]], [[1h36|1h36]], [[1h37|1h37]], [[1h39|1h39]], [[1h3a|1h3a]], [[1h3b|1h3b]], [[1h3c|1h3c]], [[1o6q|1o6q]], [[1o6r|1o6r]], [[1o79|1o79]], [[1ump|1ump]], [[1sqc|1sqc]], [[2sqc|2sqc]], [[3sqc|3sqc]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gsz|1gsz]], [[1h35|1h35]], [[1h36|1h36]], [[1h37|1h37]], [[1h39|1h39]], [[1h3a|1h3a]], [[1h3b|1h3b]], [[1h3c|1h3c]], [[1o6q|1o6q]], [[1o6r|1o6r]], [[1o79|1o79]], [[1ump|1ump]], [[1sqc|1sqc]], [[2sqc|2sqc]], [[3sqc|3sqc]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene--hopene_cyclase Squalene--hopene cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.17 5.4.99.17] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene--hopene_cyclase Squalene--hopene cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.17 5.4.99.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o6h RCSB], [http://www.ebi.ac.uk/pdbsum/1o6h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o6h RCSB], [http://www.ebi.ac.uk/pdbsum/1o6h PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Atcc 27009]]
[[Category: Atcc 27009]]
[[Category: Squalene--hopene cyclase]]
[[Category: Squalene--hopene cyclase]]
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[[Category: Aebi, J D.]]
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[[Category: Aebi, J D]]
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[[Category: Dehmlow, H.]]
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[[Category: Dehmlow, H]]
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[[Category: Lenhart, A.]]
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[[Category: Lenhart, A]]
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[[Category: Morand, O H.]]
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[[Category: Morand, O H]]
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[[Category: Reinert, D J.]]
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[[Category: Reinert, D J]]
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[[Category: Schulz, G E.]]
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[[Category: Schulz, G E]]
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[[Category: Weihofen, W A.]]
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[[Category: Weihofen, W A]]
[[Category: Cholesterol biosynthesis]]
[[Category: Cholesterol biosynthesis]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]

Revision as of 17:05, 5 January 2015

SQUALENE-HOPENE CYCLASE

1o6h, resolution 2.80Å

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