This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4nfl
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nfl RCSB], [http://www.ebi.ac.uk/pdbsum/4nfl PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nfl RCSB], [http://www.ebi.ac.uk/pdbsum/4nfl PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NT5M_HUMAN NT5M_HUMAN]] Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Brynda, J | + | [[Category: Brynda, J]] |
| - | [[Category: Pachl, P | + | [[Category: Pachl, P]] |
| - | [[Category: Rezacova, P | + | [[Category: Rezacova, P]] |
[[Category: Had-like]] | [[Category: Had-like]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Mitochondria]] | [[Category: Mitochondria]] | ||
[[Category: Nucleotidase]] | [[Category: Nucleotidase]] | ||
Revision as of 21:51, 24 December 2014
Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor NPB-T
| |||||||||||
