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4r8y
From Proteopedia
(Difference between revisions)
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| - | + | ==BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-4-(((R)-1-(2-cyclopentylacetyl)pyrrolidin-3-yl)methyl)-1-methyl-5-oxoimidazolidin-2-iminium== | |
| - | + | <StructureSection load='4r8y' size='340' side='right' caption='[[4r8y]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4r8y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R8Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3KO:(2E,5R)-5-(2-CYCLOHEXYLETHYL)-5-{[(3R)-1-(CYCLOPENTYLACETYL)PYRROLIDIN-3-YL]METHYL}-2-IMINO-3-METHYLIMIDAZOLIDIN-4-ONE'>3KO</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r91|4r91]], [[4r92|4r92]], [[4r93|4r93]], [[4r95|4r95]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r8y RCSB], [http://www.ebi.ac.uk/pdbsum/4r8y PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Memapsin 2]] | ||
| + | [[Category: Caldwell, J P.]] | ||
| + | [[Category: Orth, P.]] | ||
| + | [[Category: Strickland, C.]] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Beta-site amyloid precursor protein cleaving enzyme 1]] | ||
| + | [[Category: Beta-site app cleaving enzyme 1]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 09:00, 5 November 2014
BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-4-(((R)-1-(2-cyclopentylacetyl)pyrrolidin-3-yl)methyl)-1-methyl-5-oxoimidazolidin-2-iminium
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