We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

4ojj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 7: Line 7:
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ojj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ojj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ojj RCSB], [http://www.ebi.ac.uk/pdbsum/4ojj PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ojj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ojj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ojj RCSB], [http://www.ebi.ac.uk/pdbsum/4ojj PDBsum]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/PAT1_YEAST PAT1_YEAST]] Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation. First decay factor recruited to mRNA, at a time when the mRNA is still associated with translation factors. Subsequently, PAT1 recruits the hepta-heterodimer LSM1-LSM7 complex to P-bodies. In association with the LSM1-LSM7 complex, stabilizes the 3' terminus of mRNAs. This association is also required for mosaic virus genomic RNA translation. Modulates the rates of mRNA-decapping that occur following deadenylation. Might be required for promoting the formation or the stabilization of the preinitiation translation complexes. Required for 40S ribosomal subunit joining to capped and/or polyadenylated mRNA. With other P-body components, enhances the formation of retrotransposition-competent Ty1 virus-like particles. Necessary for accurate chromosome transmission during cell division.<ref>PMID:8816497</ref> <ref>PMID:8972867</ref> <ref>PMID:10523645</ref> <ref>PMID:10394921</ref> <ref>PMID:10747033</ref> <ref>PMID:10779343</ref> <ref>PMID:10913177</ref> <ref>PMID:11027264</ref> <ref>PMID:10761922</ref> <ref>PMID:11514438</ref> <ref>PMID:12773554</ref> <ref>PMID:16179257</ref> <ref>PMID:17875743</ref> <ref>PMID:17429074</ref> <ref>PMID:17513695</ref> <ref>PMID:18086885</ref> <ref>PMID:19901074</ref> <ref>PMID:20832728</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 21:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Back, R.]]
+
[[Category: Back, R]]
-
[[Category: Fourati-Kammoun, Z.]]
+
[[Category: Fourati-Kammoun, Z]]
-
[[Category: Gaudon-Plesse, C.]]
+
[[Category: Gaudon-Plesse, C]]
-
[[Category: Graille, M.]]
+
[[Category: Graille, M]]
-
[[Category: Keller, J.]]
+
[[Category: Keller, J]]
-
[[Category: Kolesnikova, O.]]
+
[[Category: Kolesnikova, O]]
-
[[Category: Lazar, N.]]
+
[[Category: Lazar, N]]
-
[[Category: Seraphin, B.]]
+
[[Category: Seraphin, B]]
[[Category: Arm-repeat fold]]
[[Category: Arm-repeat fold]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Dcp2]]
[[Category: Dcp2]]
[[Category: Lsm1-7]]
[[Category: Lsm1-7]]

Revision as of 17:13, 24 December 2014

X-ray structure of the C-terminal domain of Pat1 (decapping activator)

4ojj, resolution 2.32Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ojj"
Personal tools