1jhn
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1jhn |SIZE=350|CAPTION= <scene name='initialview01'>1jhn</scene>, resolution 2.9Å | |PDB= 1jhn |SIZE=350|CAPTION= <scene name='initialview01'>1jhn</scene>, resolution 2.9Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene> | + | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jhn OCA], [http://www.ebi.ac.uk/pdbsum/1jhn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jhn RCSB]</span> | ||
}} | }} | ||
| Line 29: | Line 32: | ||
[[Category: Schrag, J D.]] | [[Category: Schrag, J D.]] | ||
[[Category: Thomas, D Y.]] | [[Category: Thomas, D Y.]] | ||
| - | [[Category: CA]] | ||
[[Category: beta sandwich]] | [[Category: beta sandwich]] | ||
[[Category: jelly-roll]] | [[Category: jelly-roll]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:33:47 2008'' |
Revision as of 18:33, 30 March 2008
| |||||||
| , resolution 2.9Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of the Lumenal Domain of Calnexin
Overview
The three-dimensional structure of the lumenal domain of the lectin-like chaperone calnexin determined to 2.9 A resolution reveals an extended 140 A arm inserted into a beta sandwich structure characteristic of legume lectins. The arm is composed of tandem repeats of two proline-rich sequence motifs which interact with one another in a head-to-tail fashion. Identification of the ligand binding site establishes calnexin as a monovalent lectin, providing insight into the mechanism by which the calnexin family of chaperones interacts with monoglucosylated glycoproteins.
About this Structure
1JHN is a Single protein structure of sequence from Canis lupus familiaris. Full crystallographic information is available from OCA.
Reference
The Structure of calnexin, an ER chaperone involved in quality control of protein folding., Schrag JD, Bergeron JJ, Li Y, Borisova S, Hahn M, Thomas DY, Cygler M, Mol Cell. 2001 Sep;8(3):633-44. PMID:11583625
Page seeded by OCA on Sun Mar 30 21:33:47 2008
