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2qz5
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qz5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qz5 RCSB], [http://www.ebi.ac.uk/pdbsum/2qz5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qz5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qz5 RCSB], [http://www.ebi.ac.uk/pdbsum/2qz5 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AIDA_MOUSE AIDA_MOUSE]] Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Zheng, L S | + | [[Category: Zheng, L S]] |
[[Category: Aida]] | [[Category: Aida]] | ||
[[Category: Developmental protein]] | [[Category: Developmental protein]] | ||
[[Category: Lipid binding protein]] | [[Category: Lipid binding protein]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 20:05, 24 December 2014
Crystal Structure of the C-terminal domain of Aida
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