2zfd

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zfd RCSB], [http://www.ebi.ac.uk/pdbsum/2zfd PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zfd RCSB], [http://www.ebi.ac.uk/pdbsum/2zfd PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CNBL2_ARATH CNBL2_ARATH]] Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Binds four calcium ions per subunit. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Mediates the inactivation of the proton pump AHA2 by CIPK11. Probably involved in regulating signaling responses to abscisic acid.<ref>PMID:17483306</ref> <ref>PMID:17898163</ref> <ref>PMID:22547024</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Akaboshi, M.]]
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[[Category: Akaboshi, M]]
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[[Category: Hashimoto, H.]]
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[[Category: Hashimoto, H]]
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[[Category: Ishida, H.]]
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[[Category: Ishida, H]]
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[[Category: Koizumi, N.]]
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[[Category: Koizumi, N]]
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[[Category: Sato, M.]]
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[[Category: Sato, M]]
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[[Category: Shimizu, T.]]
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[[Category: Shimizu, T]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Calcium binding protein]]
[[Category: Calcium binding protein]]

Revision as of 01:11, 25 December 2014

The crystal structure of plant specific calcium binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14

2zfd, resolution 1.20Å

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