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2ksa
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ksa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ksa RCSB], [http://www.ebi.ac.uk/pdbsum/2ksa PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ksa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ksa RCSB], [http://www.ebi.ac.uk/pdbsum/2ksa PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NK1R_HUMAN NK1R_HUMAN]] This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. [[http://www.uniprot.org/uniprot/TKN1_HUMAN TKN1_HUMAN]] Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Gayen, A | + | [[Category: Gayen, A]] |
| - | [[Category: Mukhopadhyay, C | + | [[Category: Mukhopadhyay, C]] |
[[Category: Autodock]] | [[Category: Autodock]] | ||
[[Category: Dmpc/chaps bicelle]] | [[Category: Dmpc/chaps bicelle]] | ||
Revision as of 02:39, 25 December 2014
Substance P in DMPC/CHAPS isotropic q=0.25 bicelles as a ligand for NK1R
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