This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ks9
From Proteopedia
(Difference between revisions)
| Line 6: | Line 6: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ks9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ks9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ks9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ks9 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ks9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ks9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ks9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ks9 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NK1R_HUMAN NK1R_HUMAN]] This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. [[http://www.uniprot.org/uniprot/TKN1_HUMAN TKN1_HUMAN]] Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 21: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Gayen, A | + | [[Category: Gayen, A]] |
| - | [[Category: Mukhopadhyay, C | + | [[Category: Mukhopadhyay, C]] |
[[Category: Autodock]] | [[Category: Autodock]] | ||
[[Category: Neuropeptide receptor-neuropeptide complex]] | [[Category: Neuropeptide receptor-neuropeptide complex]] | ||
Revision as of 19:02, 24 December 2014
Solution conformation of substance P in water complexed with NK1R
| |||||||||||
