2ksg
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ksg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ksg RCSB], [http://www.ebi.ac.uk/pdbsum/2ksg PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ksg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ksg RCSB], [http://www.ebi.ac.uk/pdbsum/2ksg PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/DCD_HUMAN DCD_HUMAN]] DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.<ref>PMID:17448443</ref> Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.<ref>PMID:17448443</ref> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Jung, H | + | [[Category: Jung, H]] |
- | [[Category: Kim, J | + | [[Category: Kim, J]] |
- | [[Category: Yang, S | + | [[Category: Yang, S]] |
[[Category: Amphipathic alpha helix]] | [[Category: Amphipathic alpha helix]] | ||
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
[[Category: Antibiotic peptide]] | [[Category: Antibiotic peptide]] | ||
[[Category: Peptide-membrane interaction]] | [[Category: Peptide-membrane interaction]] |
Revision as of 22:55, 24 December 2014
Solution structure of dermcidin-1L, a human antibiotic peptide
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