2kkt
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kkt RCSB], [http://www.ebi.ac.uk/pdbsum/2kkt PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kkt RCSB], [http://www.ebi.ac.uk/pdbsum/2kkt PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AT7L3_HUMAN AT7L3_HUMAN]] Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.[HAMAP-Rule:MF_03047]<ref>PMID:18206972</ref> <ref>PMID:21746879</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Atkinson, A R | + | [[Category: Atkinson, A R]] |
| - | [[Category: Bonnet, J | + | [[Category: Bonnet, J]] |
| - | [[Category: Kieffer, B | + | [[Category: Kieffer, B]] |
| - | [[Category: Romier, C | + | [[Category: Romier, C]] |
| - | [[Category: Wang, Y | + | [[Category: Wang, Y]] |
[[Category: Activator]] | [[Category: Activator]] | ||
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
Revision as of 23:50, 24 December 2014
Solution structure of the SCA7 domain of human Ataxin-7-L3 protein
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