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2rr6

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rr6 RCSB], [http://www.ebi.ac.uk/pdbsum/2rr6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rr6 RCSB], [http://www.ebi.ac.uk/pdbsum/2rr6 PDBsum]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/AN32B_HUMAN AN32B_HUMAN]] Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.<ref>PMID:20538007</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Harada, T.]]
+
[[Category: Harada, T]]
-
[[Category: Kigawa, T.]]
+
[[Category: Kigawa, T]]
-
[[Category: Koshiba, S.]]
+
[[Category: Koshiba, S]]
-
[[Category: Tanaka, A.]]
+
[[Category: Tanaka, A]]
-
[[Category: Tochio, N.]]
+
[[Category: Tochio, N]]
-
[[Category: Tsuda, K.]]
+
[[Category: Tsuda, K]]
-
[[Category: Umehara, T.]]
+
[[Category: Umehara, T]]
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[[Category: Watanabe, S.]]
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[[Category: Watanabe, S]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama, S]]
[[Category: Acidic protein rich in leucine]]
[[Category: Acidic protein rich in leucine]]
[[Category: Gene regulation]]
[[Category: Gene regulation]]

Revision as of 06:05, 25 December 2014

Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B

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