This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4l4l
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4l RCSB], [http://www.ebi.ac.uk/pdbsum/4l4l PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4l RCSB], [http://www.ebi.ac.uk/pdbsum/4l4l PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NAMPT_HUMAN NAMPT_HUMAN]] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 23: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Nicotinamide phosphoribosyltransferase]] | [[Category: Nicotinamide phosphoribosyltransferase]] | ||
| - | [[Category: Dragovich, S P | + | [[Category: Dragovich, S P]] |
| - | [[Category: Ho, Y | + | [[Category: Ho, Y]] |
| - | [[Category: Liu, Y | + | [[Category: Liu, Y]] |
| - | [[Category: Oh, A | + | [[Category: Oh, A]] |
| - | [[Category: Wang, W | + | [[Category: Wang, W]] |
| - | [[Category: Yuen, P | + | [[Category: Yuen, P]] |
| - | [[Category: Zak, M | + | [[Category: Zak, M]] |
| - | [[Category: Zheng, X | + | [[Category: Zheng, X]] |
[[Category: Active site]] | [[Category: Active site]] | ||
[[Category: Inhibitor prpp adduct]] | [[Category: Inhibitor prpp adduct]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 18:23, 24 December 2014
Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase
| |||||||||||
