This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4u03
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u03 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u03 RCSB], [http://www.ebi.ac.uk/pdbsum/4u03 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u03 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u03 RCSB], [http://www.ebi.ac.uk/pdbsum/4u03 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DNCV_VIBCH DNCV_VIBCH]] Catalyzes the synthesis of cyclic AMP-GMP from ATP and GTP. Is also able to produce c-di-AMP and c-di-GMP from ATP and GTP, respectively; however, c-AMP-GMP is the dominant molecule produced by DncV in vivo. Is required for efficient V.cholerae intestinal colonization, and down-regulates the colonization-influencing process of chemotaxis. Is not active with dATP, TTP, UTP, and CTP. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 23: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cyclic GMP-AMP synthase]] | [[Category: Cyclic GMP-AMP synthase]] | ||
| - | [[Category: Xiang, Y | + | [[Category: Xiang, Y]] |
| - | [[Category: Zhu, D Y | + | [[Category: Zhu, D Y]] |
[[Category: Regulation]] | [[Category: Regulation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 15:47, 25 December 2014
Structure of the vibrio cholerae di-nucleotide cyclase (DncV) in complex with GTP and 5MTHFGLU2
| |||||||||||
