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4l4m
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4m RCSB], [http://www.ebi.ac.uk/pdbsum/4l4m PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l4m RCSB], [http://www.ebi.ac.uk/pdbsum/4l4m PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NAMPT_HUMAN NAMPT_HUMAN]] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Nicotinamide phosphoribosyltransferase]] | [[Category: Nicotinamide phosphoribosyltransferase]] | ||
| - | [[Category: Dragovich, S P | + | [[Category: Dragovich, S P]] |
| - | [[Category: Ho, Y | + | [[Category: Ho, Y]] |
| - | [[Category: Liu, Y | + | [[Category: Liu, Y]] |
| - | [[Category: Oh, A | + | [[Category: Oh, A]] |
| - | [[Category: Wang, W | + | [[Category: Wang, W]] |
| - | [[Category: Yuen, P | + | [[Category: Yuen, P]] |
| - | [[Category: Zak, M | + | [[Category: Zak, M]] |
| - | [[Category: Zheng, X | + | [[Category: Zheng, X]] |
[[Category: Active site]] | [[Category: Active site]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 10:13, 25 December 2014
Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase
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