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2y37
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y37 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y37 RCSB], [http://www.ebi.ac.uk/pdbsum/2y37 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y37 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y37 RCSB], [http://www.ebi.ac.uk/pdbsum/2y37 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NOS2_MOUSE NOS2_MOUSE]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.<ref>PMID:16373578</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Nitric-oxide synthase]] | [[Category: Nitric-oxide synthase]] | ||
| - | [[Category: Andrews, G | + | [[Category: Andrews, G]] |
| - | [[Category: Beaton, H G | + | [[Category: Beaton, H G]] |
| - | [[Category: Birkinshaw, T N | + | [[Category: Birkinshaw, T N]] |
| - | [[Category: Boughton-Smith, N | + | [[Category: Boughton-Smith, N]] |
| - | [[Category: Cheshire, D R | + | [[Category: Cheshire, D R]] |
| - | [[Category: Connolly, S | + | [[Category: Connolly, S]] |
| - | [[Category: Cook, T R | + | [[Category: Cook, T R]] |
| - | [[Category: Cooper, A | + | [[Category: Cooper, A]] |
| - | [[Category: Cooper, S L | + | [[Category: Cooper, S L]] |
| - | [[Category: Cox, D | + | [[Category: Cox, D]] |
| - | [[Category: Dixon, J | + | [[Category: Dixon, J]] |
| - | [[Category: Gensmantel, N | + | [[Category: Gensmantel, N]] |
| - | [[Category: Hamley, P J | + | [[Category: Hamley, P J]] |
| - | [[Category: Harrison, R | + | [[Category: Harrison, R]] |
| - | [[Category: Hartopp, P | + | [[Category: Hartopp, P]] |
| - | [[Category: Kack, H | + | [[Category: Kack, H]] |
| - | [[Category: Luker, T | + | [[Category: Luker, T]] |
| - | [[Category: Mete, A | + | [[Category: Mete, A]] |
| - | [[Category: Millichip, I | + | [[Category: Millichip, I]] |
| - | [[Category: Nicholls, D J | + | [[Category: Nicholls, D J]] |
| - | [[Category: Pimm, A D | + | [[Category: Pimm, A D]] |
| - | [[Category: St-Gallay, S A | + | [[Category: St-Gallay, S A]] |
| - | [[Category: Wallace, A V | + | [[Category: Wallace, A V]] |
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 08:28, 24 December 2014
THE DISCOVERY OF NOVEL, POTENT AND HIGHLY SELECTIVE INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE (INOS)
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Categories: Mus musculus | Nitric-oxide synthase | Andrews, G | Beaton, H G | Birkinshaw, T N | Boughton-Smith, N | Cheshire, D R | Connolly, S | Cook, T R | Cooper, A | Cooper, S L | Cox, D | Dixon, J | Gensmantel, N | Hamley, P J | Harrison, R | Hartopp, P | Kack, H | Luker, T | Mete, A | Millichip, I | Nicholls, D J | Pimm, A D | St-Gallay, S A | Wallace, A V | Drug design | Oxidoreductase
