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2xn8
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xn8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xn8 RCSB], [http://www.ebi.ac.uk/pdbsum/2xn8 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xn8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xn8 RCSB], [http://www.ebi.ac.uk/pdbsum/2xn8 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CP125_MYCTU CP125_MYCTU]] Catalyzes the C-27 hydroxylation of cholest-4-en-3-one and cholesterol and subsequently oxidizes the alcohol of the former to the cholest-4-en-3-one-27-oic acid via the aldehyde intermediate. Not required to incorporate the cholesterol side-chain carbon atoms into cellular lipids.<ref>PMID:19846551</ref> <ref>PMID:20545858</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 22: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Kells, P M | + | [[Category: Kells, P M]] |
| - | [[Category: Montellano, P R.Ortiz De | + | [[Category: Montellano, P R.Ortiz De]] |
| - | [[Category: Ouellet, H | + | [[Category: Ouellet, H]] |
| - | [[Category: Podust, L M | + | [[Category: Podust, L M]] |
[[Category: Cholesterol degradation]] | [[Category: Cholesterol degradation]] | ||
[[Category: Monooxygenase]] | [[Category: Monooxygenase]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Reverse type i inhibitor]] | [[Category: Reverse type i inhibitor]] | ||
Revision as of 20:29, 24 December 2014
X-RAY STRUCTURE OF THE SUBSTRATE-FREE MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125
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