2xky

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xky RCSB], [http://www.ebi.ac.uk/pdbsum/2xky PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xky RCSB], [http://www.ebi.ac.uk/pdbsum/2xky PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IRK2_MOUSE IRK2_MOUSE]] Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Collins, R F.]]
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[[Category: Collins, R F]]
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[[Category: Fomina, S.]]
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[[Category: Fomina, S]]
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[[Category: Golovanova, M.]]
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[[Category: Golovanova, M]]
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[[Category: Grossmann, J G.]]
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[[Category: Grossmann, J G]]
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[[Category: Howard, T D.]]
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[[Category: Howard, T D]]
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[[Category: Leyland, M L.]]
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[[Category: Leyland, M L]]
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[[Category: Prince, S M.]]
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[[Category: Prince, S M]]
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[[Category: Ryan, L O.]]
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[[Category: Ryan, L O]]
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[[Category: Sleator, O K.]]
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[[Category: Sleator, O K]]
[[Category: Ion channel]]
[[Category: Ion channel]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
[[Category: Metal transport]]
[[Category: Metal transport]]

Revision as of 03:20, 25 December 2014

Single particle analysis of Kir2.1NC_4 in negative stain

2xky, resolution 17.20Å

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