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2xur

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xur OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xur RCSB], [http://www.ebi.ac.uk/pdbsum/2xur PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xur OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xur RCSB], [http://www.ebi.ac.uk/pdbsum/2xur PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Bjoras, M.]]
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[[Category: Bjoras, M]]
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[[Category: Dalhus, B.]]
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[[Category: Dalhus, B]]
-
[[Category: Flaatten, I.]]
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[[Category: Flaatten, I]]
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[[Category: Johnsen, L.]]
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[[Category: Johnsen, L]]
[[Category: Morigen]]
[[Category: Morigen]]
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[[Category: Skarstad, K.]]
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[[Category: Skarstad, K]]
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[[Category: Waldminghaus, T.]]
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[[Category: Waldminghaus, T]]
[[Category: Dna-directed dna polymerase]]
[[Category: Dna-directed dna polymerase]]
[[Category: Replication]]
[[Category: Replication]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 04:09, 25 December 2014

THE G157C MUTATION IN THE ESCHERICHIA COLI SLIDING CLAMP SPECIFICALLY AFFECTS INITIATION OF REPLICATION

2xur, resolution 1.90Å

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