3a8y
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a8y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a8y RCSB], [http://www.ebi.ac.uk/pdbsum/3a8y PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a8y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a8y RCSB], [http://www.ebi.ac.uk/pdbsum/3a8y PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BAG5_HUMAN BAG5_HUMAN]] Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.<ref>PMID:20223214</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[BAG protein|BAG protein]] | ||
| + | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arakawa, A | + | [[Category: Arakawa, A]] |
| - | [[Category: Handa, N | + | [[Category: Handa, N]] |
| - | [[Category: Ohsawa, N | + | [[Category: Ohsawa, N]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Shirouzu, M | + | [[Category: Shirouzu, M]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Atpase domain]] | [[Category: Atpase domain]] | ||
[[Category: Bag domain]] | [[Category: Bag domain]] | ||
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[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Triple helix]] | [[Category: Triple helix]] | ||
Revision as of 14:33, 24 December 2014
Crystal structure of the complex between the BAG5 BD5 and Hsp70 NBD
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