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3aaj

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aaj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aaj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aaj RCSB], [http://www.ebi.ac.uk/pdbsum/3aaj PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aaj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aaj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aaj RCSB], [http://www.ebi.ac.uk/pdbsum/3aaj PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PDCD6_HUMAN PDCD6_HUMAN]] Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity.<ref>PMID:16132846</ref> <ref>PMID:19520058</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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==See Also==
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*[[Cell death protein|Cell death protein]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Inuzuka, T.]]
+
[[Category: Inuzuka, T]]
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[[Category: Kawasaki, M.]]
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[[Category: Kawasaki, M]]
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[[Category: Maki, M.]]
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[[Category: Maki, M]]
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[[Category: Shibata, H.]]
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[[Category: Shibata, H]]
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[[Category: Suzuki, H.]]
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[[Category: Suzuki, H]]
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[[Category: Wakatsuki, S.]]
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[[Category: Wakatsuki, S]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Calcium-binding protein]]
[[Category: Calcium-binding protein]]
[[Category: Endoplasmic reticulum]]
[[Category: Endoplasmic reticulum]]
[[Category: Penta-ef-hand protein]]
[[Category: Penta-ef-hand protein]]

Revision as of 03:54, 25 December 2014

Crystal structure of Ca2+-bound form of des3-23ALG-2deltaGF122

3aaj, resolution 2.40Å

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