2g5w
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g5w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g5w RCSB], [http://www.ebi.ac.uk/pdbsum/2g5w PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g5w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g5w RCSB], [http://www.ebi.ac.uk/pdbsum/2g5w PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/OPR3_ARATH OPR3_ARATH]] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. Required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program. In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).<ref>PMID:10973494</ref> <ref>PMID:19605548</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 12-oxophytodienoate reductase]] | [[Category: 12-oxophytodienoate reductase]] | ||
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
| - | [[Category: Bingman, C A | + | [[Category: Bingman, C A]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Fox, B G | + | [[Category: Fox, B G]] |
| - | [[Category: Han, B W | + | [[Category: Han, B W]] |
| - | [[Category: Malone, T E | + | [[Category: Malone, T E]] |
| - | [[Category: Phillips, G N | + | [[Category: Phillips, G N]] |
| - | [[Category: Wesenberg, G E | + | [[Category: Wesenberg, G E]] |
[[Category: At2g06050]] | [[Category: At2g06050]] | ||
| - | [[Category: Center for eukaryotic structural genomic]] | ||
[[Category: Cesg]] | [[Category: Cesg]] | ||
[[Category: Flavoenzyme]] | [[Category: Flavoenzyme]] | ||
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[[Category: Opr isoform 3]] | [[Category: Opr isoform 3]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Secondary messenger]] | [[Category: Secondary messenger]] | ||
| - | [[Category: Structural genomics functional follow-up study]] | ||
[[Category: Xenobiotic reductase]] | [[Category: Xenobiotic reductase]] | ||
Revision as of 18:03, 25 December 2014
X-ray crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 (AtOPR3) in complex with 8-iso prostaglandin A1 and its cofactor, flavin mononucleotide.
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Categories: 12-oxophytodienoate reductase | Arabidopsis thaliana | Bingman, C A | Structural genomic | Fox, B G | Han, B W | Malone, T E | Phillips, G N | Wesenberg, G E | At2g06050 | Cesg | Flavoenzyme | Flavoprotein | Old Yellow Enzyme | Opr isoform 3 | Oxidoreductase | PSI, Protein structure initiative | Secondary messenger | Xenobiotic reductase
