3av1
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3av1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3av1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3av1 RCSB], [http://www.ebi.ac.uk/pdbsum/3av1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3av1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3av1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3av1 RCSB], [http://www.ebi.ac.uk/pdbsum/3av1 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Kagawa, W | + | [[Category: Kagawa, W]] |
| - | [[Category: Kimura, H | + | [[Category: Kimura, H]] |
| - | [[Category: Kurumizaka, H | + | [[Category: Kurumizaka, H]] |
| - | [[Category: Miya, Y | + | [[Category: Miya, Y]] |
| - | [[Category: Osakabe, A | + | [[Category: Osakabe, A]] |
| - | [[Category: Shiga, T | + | [[Category: Shiga, T]] |
| - | [[Category: Tachiwana, H | + | [[Category: Tachiwana, H]] |
[[Category: Dna-binding protein]] | [[Category: Dna-binding protein]] | ||
[[Category: Histone-fold]] | [[Category: Histone-fold]] | ||
[[Category: Structural protein-dna complex]] | [[Category: Structural protein-dna complex]] | ||
Revision as of 18:08, 25 December 2014
The human nucleosome structure containing the histone variant H3.2
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