3aiz
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aiz RCSB], [http://www.ebi.ac.uk/pdbsum/3aiz PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aiz RCSB], [http://www.ebi.ac.uk/pdbsum/3aiz PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PCNA2_SULTO PCNA2_SULTO]] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Both trimeric complexes inhibit DNA ligase and both 3'-5' and 5'-3' activity of Hel308 (Hjm) helicase, but stimulate Hjc, the Holliday junction cleavage enzyme.[HAMAP-Rule:MF_00317]<ref>PMID:18782564</ref> [[http://www.uniprot.org/uniprot/PCNA3_SULTO PCNA3_SULTO]] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Both trimeric complexes inhibit DNA ligase and both 3'-5' and 5'-3' activity of Hel308 (Hjm) helicase, but stimulate Hjc, the Holliday junction cleavage enzyme.[HAMAP-Rule:MF_00317]<ref>PMID:18782564</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Sulfolobus tokodaii]] | [[Category: Sulfolobus tokodaii]] | ||
| - | [[Category: Higuchi, S | + | [[Category: Higuchi, S]] |
| - | [[Category: Kawai, A | + | [[Category: Kawai, A]] |
| - | [[Category: Miyamoto, S | + | [[Category: Miyamoto, S]] |
[[Category: Protein-protein complex]] | [[Category: Protein-protein complex]] | ||
[[Category: Replication]] | [[Category: Replication]] | ||
Revision as of 23:30, 24 December 2014
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)
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