2xb5
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xb5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xb5 RCSB], [http://www.ebi.ac.uk/pdbsum/2xb5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xb5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xb5 RCSB], [http://www.ebi.ac.uk/pdbsum/2xb5 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Hinrichs, W | + | [[Category: Hinrichs, W]] |
| - | [[Category: Kisker, C | + | [[Category: Kisker, C]] |
| - | [[Category: Saenger, W | + | [[Category: Saenger, W]] |
[[Category: Antibiotic resistance]] | [[Category: Antibiotic resistance]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
Revision as of 06:45, 25 December 2014
TET REPRESSOR (CLASS D) IN COMPLEX WITH 7-IODOTETRACYCLINE
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