1g62
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g62 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g62 RCSB], [http://www.ebi.ac.uk/pdbsum/1g62 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1g62 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g62 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g62 RCSB], [http://www.ebi.ac.uk/pdbsum/1g62 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1g62 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IF6_YEAST IF6_YEAST]] Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by the GTPase RIA1/EFL1 and by SDO1. Also required for pre-rRNA processing.<ref>PMID:10085284</ref> <ref>PMID:11779510</ref> <ref>PMID:11238882</ref> <ref>PMID:17353896</ref> <ref>PMID:18256024</ref> <ref>PMID:11101899</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 17:34, 25 December 2014
CRYSTAL STRUCTURE OF S.CEREVISIAE EIF6
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