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3d47

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==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and D-malate==
==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and D-malate==
<StructureSection load='3d47' size='340' side='right' caption='[[3d47]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3d47' size='340' side='right' caption='[[3d47]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d47]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D47 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d47]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D47 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3box|3box]], [[3d46|3d46]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3box|3box]], [[3d46|3d46]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yfaW, STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yfaW, STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d47 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d47 RCSB], [http://www.ebi.ac.uk/pdbsum/3d47 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3d47 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d47 OCA], [http://pdbe.org/3d47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d47 RCSB], [http://www.ebi.ac.uk/pdbsum/3d47 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d47 ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3d47 TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY]] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d47 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
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[[Category: Salty]]
[[Category: Almo, S C]]
[[Category: Almo, S C]]
[[Category: Burley, S K]]
[[Category: Burley, S K]]

Revision as of 15:04, 11 August 2016

Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and D-malate

3d47, resolution 1.80Å

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